CELL GROWTH AND DIFFERENTIATION

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GROWTH; This can best be defined in three terms
+Increase in the intercellular component of the cells (Accretionary growth)
+Increase in the size of the cells ( Auxetic growth)
+Increase in the number of cells (Multiplicative growth)
Typically growth in real practical cases usually entails the three forms.
PLURIPOTENCY OF A PRIMITIVE CELL; A primitive cell has the ability to specialize along many lines. The fate of primitive cells then depends on the interplay between the generic, cytoplasmic and environmental factors (factors which induces specialization) surrounding the cell. By implication, the cell’s fate or destiny will be affected by the environment, region it finds itself depending on the needs i.e. a primitive cell that finds itself at the eye will suddenly have to conform it protein build up to function as one of the cells in the ophthalmic region.
DIFFERENTIATION; This is the process by which a pluripotent cell becomes adapted or conform (specializes) to suite a certain role by virtue of the environment it finds itself. This environmental conditioning effect is usually permanent restricting the fate of the primitive cell and its descendants. Differentiation is different from modulation in which there is just a temporary effect as long as the cell remains in such environment.
          Differentiation is in 4 phases;
+Chemo-differentiation ; this are the initial internal changes that occurs in a primitive cell once it decides to specialize
+Cyto-differentiation; this refers to the observable cytological changes in the specializing cell
+Histo-differentiation; this refers to the coming together of various complementary cell types to form a structurally organized tissue
+Functional differentiation; this refers to the onset of functions in the tissue

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